Diltiazem and anal fissures
22 Jan Summary of the evidence on 2% topical diltiazem hydrochloride for chronic anal fissure to inform local NHS planning and decision-making.
Summary of possible benefits and harms
This leaflet aims to answer your questions about using diltiazem hydrochloride 2 % cream to treat your anal fissure. Please read this leaflet carefully before you.
Quality of life in patients with chronic anal fissure after topical treatment with diltiazem
[Treatment of chronic anal fissures: diltiazem or isosorbide dinitrate as first choice?].
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Colorectal Dis. Nov;4(6) The role of topical diltiazem in the treatment of chronic anal fissures that have failed glyceryl trinitrate therapy. Griffin N(1).
Description:Chronic anal fissure has traditionally been treated surgically. Initial enthusiasm for chemical sphincterotomy has waned because of poor outcomes with glyceryl trinitrate ointment. In this study the use of topical 2 per cent diltiazem ointment has been investigated as an alternative method of chemical sphincterotomy.